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DEVICE AND METHOD FOR MAKING ELECTRICAL CONTACT WI

来源:华佗小知识
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专利名称:DEVICE AND METHOD FOR MAKING

ELECTRICAL CONTACT WITH BIOLOGICALCELLS SUSPENDED IN A FLUID

发明人:STETT, ALFRED,HAEMMERLE, HUGO,NISCH,

WILFRIED,KNOTT, THOMAS

申请号:EP01962833.8申请日:20010705公开号:EP1311655B1公开日:20060607

摘要:The invention relates to a device for making electrical contact with biologicalcells (11), suspended in a fluid (14), comprising a substrate with at least one opening anda means of immobilising a cell (11) on the opening. Furthermore, an electrode for makingelectrical contact with the immobilised cell (11) is provided. A contact unit with a contactpoint (23) is arranged at the opening, the upper end of which extends into the opening,such that the said end contacts the cell membrane of an immobilised cell (11). Thecontact point (23) comprises a contact channel opening at the upper end thereof, bymeans of which a hydrodynamic vacuum may be played on the cell membrane and theelectrode is in electrical contact with the contact channel. The invention further relates toa method for making electrical contact with biological cells suspended in a fluid, wherebya cell is immobilised above an opening in a substrate and the cell contacted by at leastone electrode. In order to make contact with the immobilised cell (11), a contact point(23), extending through the opening, produces a hydrodynamic vacuum on the cellmembrane of the cell (11), whereby the electrode makes electrical contact with the cell

(11) by means of the contact point (23).

申请人:NMI NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DERUNIVERSITAET TUEBINGEN,NMI UNIV TUEBINGEN,NMI NATURWISSENSCHAFTLICHESUND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN

地址:DE

国籍:DE

代理机构:Duhme, Torsten

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