专利内容由知识产权出版社提供
专利名称：Closed-loop drug delivery system发明人：William L. Rohr,Alan J. Dextradeur,David D.
Konieczynski
申请号：US10092955申请日：20020306
公开号：US20030171711A1公开日：20030911
专利附图：
摘要：A delivery system for a drug or bioactive agent includes an implantable pumpand a delivery conduit that may be implanted in an organ or other tissue (e.g., the centralor the peripheral nervous system) of a subject. A sensor is also implanted, and a
controller unit receives the sensor output and directs drug delivery from within thepatient pump accordingly. The sensor directly measures a primary biochemical materialor state in the tissue or organ system, and the monitoring unit effects closed loopfeedback control of the pump to achieve a desired end. The end may be the regulation ofmetabolism or maintenance of a stable metabolic or other state, or may be treatmentregimen, e.g., by delivery of a dosage level or distribution of a drug in specific brain ornervous an system tissue. The sensed material may be the agent itself, a metabolite, or arelated native material, tissue state or condition.
申请人：ROHR WILLIAM L.,DEXTRADEUR ALAN J.,KONIECZYNSKI DAVID D.
更多信息请下载全文后查看
