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Variants derived from ActRIIB and uses therefor

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专利名称:Variants derived from ActRIIB and uses

therefor

发明人:Knopf, John,Kumar, Ravindra,Seehra, Jasbir申请号:EP14175663.5申请日:20080204公开号:EP2805967A1公开日:20141126

专利附图:

摘要:The present invention provides a variant ActRIIB protein comprising an aminoacid sequence that is at least 90% identical to amino acids 29-109 of SEQ ID NO:2, whereinthe protein comprises an acidic amino acid at the position corresponding to position 79 of

SEQ ID NO: 2.

申请人:Acceleron Pharma, Inc.

地址:128 Sidney Street Cambridge, MA 02139 US

国籍:US

代理机构:Lee, Nicholas John

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