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专利名称：Variants derived from ActRIIB and uses
therefor
发明人：Kumar, Ravindra,Knopf, John,Seehra, Jasbir申请号：AU2008214375申请日：20080204公开号：AU2008214375B2公开日：20130509
摘要：In certain aspects, the present invention provides compositions and methodsfor modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage,muscle, fat, and/or neuronal tissue. The present invention also provides methods ofscreening compounds that modulate activity of an ActRIIB protein and/or an ActRIIBligand. The compositions and methods provided herein are useful in treating diseasesassociated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
申请人：Acceleron Pharma Inc.
代理人：Shelston IP
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