专利内容由知识产权出版社提供
专利名称：VARIANTS DERIVED FROM ACTRIIB AND
USES THEREFOR
发明人：JOHN KNOPF,JASBIR SEEHRA,RAVINDRA
KUMAR
申请号：US123976申请日：20100929
公开号：US20110092670A1公开日：20110421
摘要：In certain aspects, the present invention provides compositions and methodsfor modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage,muscle, fat, and/or neuronal tissue. The present invention also provides methods ofscreening compounds that modulate activity of an ActRIIB protein and/or an ActRIIBligand. The compositions and methods provided herein are useful in treating diseasesassociated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
申请人：JOHN KNOPF,JASBIR SEEHRA,RAVINDRA KUMAR
地址：CARLISLE MA US,LEXINGTON MA US,ACTON MA US
国籍：US,US,US
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