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专利名称：USE OF ALPHA, BETA UNSATURATED ARYL
SULFONES FOR PROTECTING CELLS ANDTISSUES FROM IONIZING RADIATIONTOXICITY
发明人：REDDY, Premkumar, E.,REDDY, Ramana,
M.V.,COSENZA, Stephen, C.,HELSON,Lawrence
申请号：EP02733811.0申请日：20020228公开号：EP1370253B8公开日：20081126
摘要：Pre-treatment with α, β unsaturated aryl sulfones protects normal cells fromthe toxic side effects of ionizing radiation. Administration of a radioprotective α, βunsaturated aryl sulfone compound to a patient prior to anticancer radiotherapy reducesthe cytotoxic side effects of the radiation on normal cells. The radioprotective effect ofthe α, β unsaturated aryl sulfone allows the clinician to safely increase the dosage ofanticancer radiation. In some instances, amelioration of toxicity following inadvertentradiation exposure may be mitigated with administration of α, β unsatured arylsulfone.
申请人：UNIV TEMPLE,ONCONOVA THERAPEUTICS INC
地址：US,US
国籍：US,US
代理机构：Ouzman, Beverley Nicola Claire
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